2-Ethyl-1H-imidazole-4-carboxylate monohydrate

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2-Ethyl-1H-imidazole-4-carboxyl­ate monohydrate

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This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine and a nitrile oxide functionality. The latter reacts with an immobilized thiourea to yield an isothiocyanate which upon elimination generates ...

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2,4,5-Tri-4-pyridyl-1H-imidazole monohydrate

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2,4,5-Tris(pyridin-4-yl)-1H-imidazole monohydrate

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Ethyl 2-(4-bromophenyl)-1-[3-(1H-imidazol-1-yl)prop­yl]-1H-benzimidazole-5-carboxyl­ate monohydrate

In the title compound, C(22)H(21)BrN(4)O(2)·H(2)O, the two pyrazole rings are essentially planar [maximum deviations 0.002 (1) and 0.002 (1) Å], and form a dihedral angle of 73.46 (9)°. The dihedral angle between the benzene rings is 29.33 (7)°. In the crystal, mol-ecules are connected via C-H⋯O and O-H⋯N hydrogen bonds, forming layers in the ab plane.

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2011

ISSN: 1600-5368

DOI: 10.1107/s1600536811010774